Table 1.

Oral human equivalent CBD doses from mouse and rat intraperitoneal doses

Mouse to Human CBD Dose Conversion		Rat to Human CBD Dose Conversion
Mouse Dose (mg·kg-1, i.p.)	HED (mg, p.o.)	Rat Dose (mg·kg-1, i.p.)	HED (mg, p.o.)
1	34	1	68
5	170	5	340
10	341	10	681
20	681	20	1362
30	1021	30	2043
60	2043	60	4086

Each HED is based on a body mass of 60 kg and calculated as per the methods described in 2.3 Dose Conversions. The highest documented acute oral CBD dose in humans is 6000 mg; the highest documented chronic oral CBD dose in humans is 1500 mg [169]. HED: Human Equivalent Dose; i.p.: Intraperitoneal; p.o.: Oral