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. 2020 Jul 6;11:3368. doi: 10.1038/s41467-020-17002-0

Table 1.

Genetic correlation between migraine and blood pressure.

Method Trait 1 Trait 2 rg P* gcov gcov_se
LDSC Any migraine DBP 0.11 3.56 × 10−06 0.018 0.009
SBP 0.06 0.01 0.004 0.009
PP −0.01 0.75 −0.009 0.008
Migraine with aura DBP 0.17 1.50 × 10−03 −0.006 0.008
SBP 0.10 0.04 −0.014 0.008
PP 0.00 0.92 −0.015 0.007
Migraine without aura DBP 0.14 1.20 × 10−03 0.014 0.008
SBP 0.03 0.43 0.010 0.008
PP −0.08 0.06 0.002 0.007
GNOVA Any migraine DBP 0.12 3.45 × 10−07 0.009 0.002
SBP 0.07 4.64 × 10−03 0.005 0.002
PP 0.00 0.94 0.000 0.002
Migraine with aura DBP 0.15 1.90 × 10−05 0.008 0.002
SBP 0.10 2.57 × 10−03 0.006 0.002
PP 0.03 0.33 0.002 0.002
Migraine without aura DBP 0.13 1.86 × 10−04 0.008 0.002
SBP −0.02 0.66 −0.001 0.002
PP −0.12 2.12 × 10−04 −0.006 0.002

rg Genetic correlation, gcov genetic covariance, gcov_se standard error of genetic covariance, LDSC LD score regression, GNOVA genetic covariance analyzer, DBP diastolic blood pressure, SBP systolic blood pressure, PP pulse pressure.

*P-value was calculated for the genetic correlation in LDSC and for the genetic covariance in GNOVA, P-values are based on two-sided Wald test.