FIGURE 1.

a) Clinical and biological features of anti-MDA5 syndrome. b) Cytokines whose levels are increased in anti-MDA5 syndrome patients' serum. c) High-resolution computed tomography of an anti-MDA5 syndrome patient, showing bilateral peripheral subpleural ground-glass opacities prevailing in the lower lobes (arrows), with limited consolidation (arrowheads). ILD: interstitial lung disease; ARDS: acute respiratory distress syndrome; CRP: C-reactive protein; CK: creatine kinase; TNF-α: tumour necrosis factor-α; IL: interleukin; s-IL-2R: soluble IL-2 receptor; IFN-I: interferon type I.