Table 3.
Soluble mediator correlations with VACS index scores.
| Parameter | VACS | |
|---|---|---|
| Unadjusted | EDI adjusted | |
| Correlation coefficient (p-value) | ||
| Neopterin (nMol/L) | 0.40 (0.007) | 0.43 (0.004) |
| IP-10 (pg/mL) | 0.30 (0.051) | 0.29 (0.055) |
| sCD163 (pg/mL) | 0.03 (0.840) | 0.08 (0.637) |
| sCD14 (pg/mL) | −0.04 (0.781) | −0.07 (0.674) |
| MCP-1 (pg/mL) | 0.18 (0.242) | 0.15 (0.327) |
| Gal-1 (pg/mL) | 0.30 (0.053) | 0.28 (0.064) |
| Gal-3 (pg/mL) | 0.18 (0.249) | 0.20 (0.208) |
| Gal-9 (pg/mL) | 0.38 (0.012) | 0.41 (0.006) |
| D-dimer (pg/mL) | 0.25 (0.101) | 0.27 (0.075) |
| CRP (pg/mL) | −0.09 (0.587) | −0.09 (0.561) |
| Cystatin C (pg/mL) | 0.54 (0.0002) | 0.53 (0.0003) |
| IL-6 (pg/mL) | 0.17 (0.291) | 0.16 (0.312) |
| TNF-α (pg/mL) | 0.27 (0.082) | 0.27 (0.080) |
| TNFRI (pg/mL) | 0.50 (0.0007) | 0.48 (0.002) |
Soluble markers were log-transformed prior to Pearson correlation and multivariate analysis. EDI, estimated duration of infection. Significant values are bold.