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. 2020 Jun 30;11:1361. doi: 10.3389/fimmu.2020.01361

Figure 2.

Figure 2

Effect of C-L on the body weight (A) and DAI (B). The EHEC+C-LL, EHEC+C-LM, EHEC+C-LH, and EHEC+Enro groups were orally administered 100 μL sterile PBS containing 1 × 108 CFUs EHEC O157:H7 and then treated by i.p. injection with 4, 8 mg/kg, or 16 mg C-L/kg body weight C-L, or 8 mg Enro/kg body weight, respectively, once/day for 3 days. The control and EHEC groups were orally administered 100 μL sterile PBS or 100 μL sterile PBS containing 1 × 108 CFUs EHEC O157:H7, respectively, without any follow-up treatments. The DAI value was derived from scores relating to weight loss, stool consistency, and occult blood. The data are shown as the mean ± standard deviation (n = 12). NS, P > 0.05; *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001.