FIGURE 6.

Average alveolar septal wall thickness (A), number of patent alveoli N(alv) (B), number of flooded alveoli N(flood) (C), total number of alveoli with discernable structure N(alv,total) = N(alv) + N(flood) (D), and the number-weighted mean alveolar volume V_n(alv) (E) for the control (black lines) and VILI (gray lines) mice fixed at airway pressures Paw = 2, 5, and 10 cmH₂O. Points plotted with the alveolar surface area to volume ratio [S/V(alv), (F)] depict the S/V for a sphere with volume V_n(alv). Significant differences from Paw = 2 cmH₂O (#), Paw = 5 cmH₂O (%), Paw = 10 cmH₂O (&) in the same treatment group. Significant difference at the same airway pressure between treatment groups is shown with asterisks. n = 5 for each point and the error bars show standard error.