TABLE 2.

Results from regression analysis predicting log-transformed H, G, or Rn from derecruitability test PEEP ($D_{rec}^{PEEP}$) with factors $D_{rec}^{PEEP0}$, $D_{rec}^{PEEP3}$, and $D_{rec}^{PEEP6}$; the log-transformed continuous time within the derecruitability test (t); and an Injury factor describing if the measurements were recorded at the start of the experiment (pre-ventilation) or after ventilation to a doubling of pulmonary system elastance (VILI).

	H		G		Rn
Predictor	Estimate (SE)	p-value	Estimate (SE)	p-value	Estimate (SE)	p-value
Intercept	3.083 (0.034)	<0.0001	0.500 (0.062)	<0.0001	−1.103 (0.057)	<0.0001
t	0.038 (0.006)	<0.0001	−0.002 (0.015)	0.8857	0.035 (0.009)	0.0002
$D_{rec}^{PEEP3}$	−0.386 (0.036)	<0.0001	0.228 (0.075)	0.0024	−0.499 (0.009)	<0.0001
$D_{rec}^{PEEP6}$	−0.229 (0.036)	<0.0001	0.580 (0.075)	<0.0001	−0.657 (0.047)	<0.0001
VILI	0.642 (0.036)	<0.0001	0.778 (0.075)	<0.0001	0.146 (0.047)	0.0021
$t\times D_{rec}^{PEEP3}$	−0.012 (0.008)	0.1529	0.002 (0.021)	0.8910	−0.016 (0.013)	0.2292
$t\times D_{rec}^{PEEP6}$	−0.014 (0.008)	0.1088	0.001 (0.021)	0.9627	−0.032 (0.013)	0.0138
t×VILI	0.060 (0.008)	<0.0001	0.115 (0.021)	<0.0001	0.008 (0.013)	0.5550
$D_{rec}^{PEEP3}\times \text{VILI}$	−0.309 (0.051)	<0.0001	−0.710 (0.106)	<0.0001	−0.176 (0.067)	0.0089
$D_{rec}^{PEEP6}\times \text{VILI}$	−0.279(0.051)	<0.0001	−0.623 (0.106)	<0.0001	−0.298 (0.067)	<0.0001
$t\times D_{rec}^{PEEP3}\times \text{VILI}$	−0.031 (0.012)	0.0100	−0.093 (0.030)	0.0015	0.002 (0.019)	0.9034
$t\times D_{rec}^{PEEP6}\times \text{VILI}$	−0.051 (0.012)	<0.0001	−0.097 (0.030)	0.0009	−0.009 (0.019)	0.6143

Fifteen mice are in each group.