Table 2.
Comparison of the clinical course between the organ and cold culture groups.
| Factors | Organ culture | Cold culture | P-value |
|---|---|---|---|
| Baseline ECD (cells/mm2) (mean ± SD) | 2,734 ± 9 (n = 636) | 2,663 ± 15 (n = 197) | < 0.001 |
| ECD 1 month after surgery (cells/mm2) (mean ± SD) | 1766 ± 20 (n = 287) | 1872 ± 37 (n = 84) | 0.012 |
| ECD 3 months after surgery (cells/mm2) (mean ± SD) | 1752 ± 23 (n = 246) | 1773 ± 41 (n = 78) | 0.661 |
| ECD 6 months after surgery (cells/mm2) (mean ± SD) | 1712 ± 21 (n = 303) | 1833 ± 40 (n = 86) | 0.001 |
| ECD 12 months after surgery (cells/mm2) (mean ± SD) | 1681 ± 21 (n = 357) | 1741 ± 39 (n = 108) | 0.179 |
| ECD loss rates at 12 months (%) | 38.3 ± 0.8 (n = 357) | 34.7 ± 1.4 (n = 108) | 0.022 |
| Preoperative BCVA (LogMAR) | 1.16 ± 0.03 (n = 527) | 1.15 ± 0.06 (n = 156) | 0.929 |
| Postoperative BCVA (LogMAR) at 1 month | 0.30 ± 0.01 (n = 562) | 0.33 ± 0.02 (n = 172) | 0.201 |
| Postoperative BCVA (LogMAR) at 3 months | 0.18 ± 0.01 (n = 396) | 0.23 ± 0.02 (n = 116) | 0.002 |
| Postoperative BCVA (LogMAR) at 6 months | 0.14 ± 0.01 (n = 391) | 0.13 ± 0.01 (n = 107) | 0.551 |
| Postoperative BCVA (LogMAR) at 12 months | 0.11 ± 0.01 (n = 394) | 0.11 ± 0.01 (n = 114) | 0.540 |
| Preoperative CCT (μm) | 661.1 ± 6.4 (n = 365) | 666.4 ± 11.4 (n = 117) | 0.865 |
| Postoperative CCT at 1 month (μm) | 554.9 ± 9.1 (n = 137) | 594.2 ± 16.2 (n = 43) | 0.036 |
| Postoperative CCT at 3 months (μm) | 534.7 ± 4.8 (n = 136) | 525.0 ± 8.3 (n = 45) | 0.315 |
| Postoperative CCT at 6 months (μm) | 538.4 ± 4.8 (n = 180) | 516.7 ± 8.9 (n = 53) | 0.034 |
| Postoperative CCT at 12 months (μm) | 535.3 ± 2.9 (n = 242) | 532.8 ± 5.0 (n = 82) | 0.667 |
| Re-bubbling; yes (+) (%) | 255 (40.0) (n = 637) | 68 (34.5) (n = 197) | 0.165 |
| Immune rejection (+) (%) | 7 (1.9) (n = 637) | 7 (3.55) (n = 197) | 0.019 |
ECD endothelial cell density, SD standard deviation, BCVA best-corrected visual acuity, logMAR logarithm of the minimal angle of resolution, CCT central corneal thickness.