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. 2020 Jul 6;6:56. doi: 10.1038/s41420-020-0290-3

Table 3.

Significant changing transcription factors in DCA-treated GES-1 cell line.

Gene symbol Fold Description
ATF3 6.27 Activating transcription factor 3
ATF4 4.73 Activating transcription factor 4
CEBPA 4.7 CCAAT enhancer binding protein-α
CEBPB 5.07 CCAAT enhancer binding protein-β
CEBPG 5.99 CCAAT enhancer binding protein-γ
E2F1 2.54 E2F transcription factor 1
E2F6 2.69 E2F transcription factor 6
EGR1 5.49 Early growth response 1
ELK1 2.06 ETS transcription factor ELK1
ESR1 2.42 Estrogen receptor 1
FOS 3.31 Fos proto-oncogene
FOXA2 2.42 Forkhead box A2
FOXG1 2.42 Forkhead box G1
GATA1 2.42 GATA-binding protein 1
GATA3 2.42 GATA-binding protein 3
GTF2B 2.19 General transcription factor IIB
HAND1 2.42 Heart and neural crest derivatives expressed 1
HNF1A 2.42 HNF1 homeobox A
HNF4A 2.53 Hepatocyte nuclear factor 4α
HSF1 2.53 Heat shock transcription factor 1
IRF1 3.71 Interferon regulatory factor 1
JUNB 2.19 JunB proto-oncogene
MAX 2.34 MYC-associated factor X
MEF2A 3.08 Myocyte enhancer factor 2A
MEF2C 2.42 Myocyte enhancer factor 2C
MYC 3.74 MYC proto-oncogene, bHLH transcription factor
MYF5 2.42 Myogenic factor 5
MYOD1 2.42 Myogenic differentiation 1
NFATC2 2.42 Nuclear factor of activated T cells 2
NFKB1 2.4 Nuclear factor-κB subunit 1
PAX6 2.42 Paired box 6
POU2AF1 2.42 POU class 2 homeobox associating factor 1
PPARA 2.66 Peroxisome proliferator activated receptor-α
PPARG 3.59 Peroxisome proliferator activated receptor-γ
RELB 9.33 RELB proto-oncogene, NF-kB subunit
SMAD1 17.72 SMAD family member 1
STAT1 12.53 Signal transducer and activator of transcription 1
STAT2 4.78 Signal transducer and activator of transcription 2
TP53 3.13 Tumor protein p53
B2M 2.37 β-2-Microglobulin
ID1 −6.67 Inhibitor of DNA binding 1, HLH protein
SMAD9 −2.41 SMAD family member 9
TFAP2A −2.48 Transcription factor AP-2α
ACTB −4.34 Actin-β

DCA deoxycholic acid.