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. 2020 Jul 6;7:212. doi: 10.1038/s41597-020-0555-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Illustration of benchmark data collection. (a) Benchmark data for influenza virus. The HI-test data for both IAV A/H3N2 and IBV were collected from reports of international organizations and published articles with pre-processed antigenic distances. The sequence data of HA proteins were collected from multiple virus databases. (b) Benchmark data of DENV. Antisera data were collected from African green monkeys, and envelope protein sequences were collected from NCBI virus databases.