Table 2.

MiRNAs known to modulate chemoresistance through regulating autophagy.

MiRNA	Target	MiRNA regulated autophagy	Autophagy regulated resistance	Drug	Reference
MiR-185		Positively	Positively		(26)
MiR-494	mTOR	Positively	Positively	Sorafenib	(27)
MiR-129-3p	Nrf2, mTOR	Positively	Positively	HDACis	(28)
MiR-142-3p	ATG5/ATG16L1	Positively	Positively	Sorafenib	(29)
MiR-26b	LC3-II, P62	Positively	Positively	5-FU	(30)
MiR-26a/b	ULK1	Negatively	Positively	Doxorubicin	(31)
MiR-101		Negatively	Positively	Cisplatin	(32)
MiR-199a-5p		Negatively	Positively	Cisplatin	(33)
MiR-375		Negatively	Positively	Sorafenib	(35)
MiR-520b	ATG7	Negatively	Positively	Doxorubicin	(36)
MiR-30a	Beclin1, ATG5	Negatively	Positively	Sorafenib	(37)

miRNAs, microRNAs; HDACis, histone deacetylase inhibitors; 5-FU, 5-fluorouracil.