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. 2020 Jun 30;11:596. doi: 10.3389/fphys.2020.00596

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Copyright © 2020 Jiang, Yang, Zhang, Song, Liu and Lv.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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EX527 abolished GYY4137-induced suppression of the oxidative stress level in diabetic lung IR injury. (A) SOD concentration. (B) T-AOC concentration. (C) MDA concentration. (D) Representative blots. (E) Nuclear Nrf2 expression. (F) HO-1 expression. (G) The ratio of Ac-Nrf2/Nrf2. Ac-Nrf2, acetylated erythroid 2-related factor 2; Nrf2, Erythroid 2-related factor 2; HO-1, heme oxygenase 1 (^ccP < 0.01 versus DM + sham group, ^ddP < 0.01 versus DM + IR group, ^eP < 0.05 versus DM + IR + H group/^eeP < 0.01 versus DM + IR + H group; n = 8 in each group).