TABLE 2.

Differences of [¹⁸F]-APN-1607 regional SUVR between AD and NC groups.

VOI	SUVR		P	Cohen d
	AD	NC
Frontal lobe	1.43 ± 0.42	0.85 ± 0.06	< 0.001***	1.926
Temporal lobe	1.64 ± 0.50	0.91 ± 0.06	< 0.001***	2.062
Occipital lobe	1.58 ± 0.47	0.95 ± 0.06	< 0.001***	1.917
Parietal lobe	1.62 ± 0.60	0.87 ± 0.06	< 0.001***	1.773
Insula	1.31 ± 0.41	0.85 ± 0.07	< 0.001***	1.546
Cingulum	1.47 ± 0.46	0.89 ± 0.05	< 0.001***	1.801
Caudate	0.91 ± 0.17	0.80 ± 0.04	0.015*	0.898
Putamen	1.18 ± 0.22	0.94 ± 0.05	< 0.001***	1.508
Pallidum	1.11 ± 0.19	1.05 ± 0.08	0.295	0.376
Thalamus	1.21 ± 0.23	1.27 ± 0.12	0.374	0.325
Midbrain	0.91 ± 0.17	1.04 ± 0.05	0.008**	1.005
Pons	0.85 ± 0.17	1.03 ± 0.06	< 0.001***	1.397
Medulla	0.72 ± 0.18	0.95 ± 0.11	< 0.001***	1.537

For SUVR, the expression means mean ± standard deviation. VOI, volume of interest; SUVR, standard uptake value ratio; AD, Alzheimer’s disease; NC, normal control. *P < 0.05, **P < 0.01, ***P < 0.001.