TABLE 4.
Brain regions with significant increased uptakes of [18F]-APN-1607 in AD group compared to NC Group (P < 0.01, FWE corrected).
| Region* | Hemisphere | Cluster size (mm3) | Z max | Coordinates† |
||
| X | Y | Z | ||||
| Fusiform gyrus (BA 37) | Left | 283,064 | 5.72 | −48 | −44 | −18 |
| Superior temporal gyrus (BA 21) | Right | 283,064 | 5.53 | 62 | −22 | −4 |
| Inferior temporal gyrus (BA 20) | Left | 283,064 | 5.50 | −54 | −24 | −22 |
| Middle frontal gyrus (BA 8) | Right | 56,784 | 5.17 | 22 | 38 | 34 |
| Middle frontal gyrus (BA 8) | Right | 56,784 | 5.17 | 30 | 30 | 34 |
| Middle frontal gyrus (BA 9) | Right | 56,784 | 5.13 | 10 | 48 | 18 |
| Middle frontal gyrus (BA 8) | Left | 51,360 | 5.06 | −10 | 38 | 34 |
| Middle frontal gyrus (BA 11) | Left | 51,360 | 5.05 | −26 | 48 | −14 |
| Cingulate gyrus (BA 12) | Left | 51,360 | 5.03 | −10 | 26 | 42 |
*Significant at FWE-corrected voxel threshold of P < 0.01, extent threshold = 58 voxels (464 mm3). †Coordinates are displayed in MNI standard space. BA, Brodmann area; FWE, familywise error.