Table 3.
Comparison of clinical features between patients with and without recurrence.
| Recurrent/metastasis (n = 26) | Not recurrent (n = 139) | p value | |
|---|---|---|---|
| Gender | |||
| Male | 24 (92.3) | 121 (87.1) | 0.45 |
| Female | 2 (7.7) | 18 (12.9) | |
| Age | |||
| median | 56 | 60 | 0.84 |
| Mean ± SD | 58.16 ± 13.60 | 58.11 ± 11.98 | |
| AJCC T stage | |||
| T1 | 0 (0) | 25 (18.0) | 0.006 |
| T2 | 2 (7.7) | 25 (18.0) | |
| T3 | 9 (34.6) | 51 (36.7) | |
| T4 | 15 (57.7) | 38 (27.3) | |
| AJCC N stage | |||
| N0 | 4 (15.4) | 49 (35.3) | 0.16 |
| N1 | 3 (11.5) | 16 (11.5) | |
| N2 | 4 (15.4) | 23 (16.5) | |
| N3 | 15 (57.7) | 51 (36.7) | |
| AJCC TNM stage | |||
| I | 2 (7.7) | 37 (26.6) | 0.025 |
| II | 3 (11.5) | 29 (20.9) | |
| III | 21 (80.8) | 73 (52.5) | |
| Neural invasion | |||
| No | 3 | 49 | |
| Yes | 23 | 90 | 0.017 |
| Lymphovascular invasion | |||
| No | 3 | 63 | |
| Yes | 23 | 76 | 0.001 |
| Size (cm) | |||
| Median | 5 | 4 | |
| Mean ± SD | 5.52 ± 2.44 | 4.48 ± 2.16 | 0.04 |
| MMR (n = 131) | |||
| dMMR | 0 (0) | 2 (1.9) | |
| pMMR | 25 (100) | 104 (98.1) | 0.13 |
| Lauren classification (n = 145) | |||
| Diffuse | 11 (52.4) | 32 (25.8) | 0.045 |
| Intestinal | 5 (23.8) | 40 (32.3) | |
| Mix | 5 (23.8) | 52 (41.9) | |
| EBV-DNA (copies/ml) | |||
| Median | 25250 | 0 | 0.003 |
Data were present as n (%) unless specified.
AJCC, American Joint Committee on Cancer; dMMR, mismatch repair deficiency; MMR, mismatch repair; pMMR, mismatch repair proficient; SD, standard deviation; TNM, tumor-node-metastasis.