Fig. 2.

Protein expression of Cx37, Cx40 and Cx43 in rPAFs and rPASMCs. In rPAFs, hypoxia increased Cx37 (a) and Cx43 (b) protein expression, while Cx40 expression was unchanged (c). In rPASMCs, hypoxia decreased Cx37 expression under 1% serum conditions (d). Cx43 expression was unchanged by hypoxia in rPASMCs (e), and decreased Cx40 expression was observed under both serum free and 1% serum conditions (f). Data expressed as mean ± SEM, and analysis was carried out by two-way ANOVA with a Tukey post hoc test. *p < 0.05, **p < 0.01, n = 4–5.

rPAF: rat pulmonary artery fibroblasts; rPASMC: rat pulmonary artery smooth muscle cells; Cx37: connexin 37; Cx43: connexin 43; Cx40: connexin 40.