Table 3.

Stepwise multivariate linear regression between clinical variables (EDSS, 25-FWT, C-EO, and C-EC) and MRI features in MS patients.

	Model				Predictive variables
Dependent variable	N	Adj R2	F	p	Variable	β	p
EDSS	1	0.229	14.99	<0.001	LV	0.496	<0.001
	2	0.350		<0.001	LV	0.435	<0.001
					Lobule VIIIb	−0.368	<0.01
25-FWT	1	0.325	23.62	<0.001	Lobule VIIIb	−0.583	<0.001
	2	0.392	16.16	<0.001	Lobule VIIIb	−0.452	<0.001
					WMV	−0.310	<0.05
C-EO	1	0.217	14.01	<0.001	Lobules I–IV	−0.483	<0.001
	2	0.298	10.98	<0.001	Lobules I–IV	−0.424	<0.01
					WMV	−0.313	<0.05
	3	0.354	9.57	<0.001	Lobules I–IV	−0.375	<0.01
					WMV	−0.278	<0.05
					LV	0.267	<0.05
C-EC	1	0.158	9.84	<0.01	Lobules I–IV	−0.420	<0.01
	2	0.223	7.74	<0.01	Lobules I–IV	−0.360	<0.01
					LV	−0.289	<0.05

Each model is adjusted for age, gender, body mass index and intracranial volume. EDSS, Expanded Disability Status Scale; 25-FWT, 25-ft walking test; C-EO, displacement of body center of pressure with eyes open; C-EC, displacement of body center of pressure with eyes closed.