Table 2.
Classification of different antimicrobial peptides according to their membrane targeting mechanism of action.
Pore-forming models | Example of AMP | Origin |
---|---|---|
Barrel-Stave | Ceratotoxin Alamethicin Amphotricin B |
Ceratitis capitate (Mediterranean fruit fly) Trichoderma viride (fungus) Streptomyces nodosu (bacteria) |
Toroidal | Melittin LL-37 Piscidin Pardaxin |
Xenopus Laevis (African clawed frog) Homo sapiens Morone Saxtilis (Atlantic striped bass) Pardarchirus marmoratus (Finless sole fish) |
Carpet-like | Magainin 2 RL-37 Cecropins Dermaseptins Ovispirin Mastoparan X |
Xenopus Laevis (African clawed frog) Macaca mulatta (Rhesus macaque) Hyalophora cecropia (North American moth) Phyllomedusa spp. (Frogs genus) Ovis aries (Sheep) Vespa xanthoptera (Japanese yellow hornet) |
AMP, antimicrobial peptide.