Table 3.

Example of peptides with their spectrum of activity.

Targeted microbes/PAMP	Examples of AMP
Gram-negative and –positive bacteria	IB-367, protegrin, MSI-78, gramicidin S, indolicidin, CEMA
Gram-negative bacteria Gram-positive bacteria	Polymyxin B HNP1, sPLA2-IIA
Fungi	Protegrin, indolicidin, gramicidin S, CEMA, polyphemusin, sPLA2-V
Virus	Indolicidin, protegrin, polyphemusin
Parasite	Magainin II, indolicidin
Endotoxin*	CEMA, polyphemusin variants

AMP, Antimicrobial peptide; PAMP, Pathogen-associated molecular pattern.

^*Endotoxin named also LPS, is a PAMP present in the cell wall of Gram-negative bacteria.