Table 1.

Cerebral pathologies in the different brain regions.

Cerebral pathology	Brain region	Affected animals	Mean number	Standard deviation	Min	Max
Total erythrocyte thrombi	Whole brain	100%/n = 24	179.60	303.2	8	1,392
	Cortex	95.8%/n = 23	98.00	237.2	0	1,043
	Basal ganglia	91.7%/n = 22	22.70	30.5	0	115
	Hippocampus	100%/n = 24	32.00	35.7	3	144
	Corpus callosum	70.8%/n = 17	9.00	19.9	0	75
	Thalamus	95.8%/n = 23	17.40	25.3	0	118
Arteriolar erythrocyte thrombi	Whole brain	87.5%/n = 21	12.10	12.8	0	41
	Cortex	58.3%/n = 14	3.30	4.1	0	11
	Basal ganglia	62.3%/n = 15	2.70	4.1	0	15
	Hippocampus	62.3%/n = 15	4.00	5.3	0	17
	Corpus callosum	29.2 %/n = 7	0.50	0.9	0	3
	Thalamus	50.0%/n = 12	2.10	3.0	0	9
Small perivascular bleeds	Whole brain	25%/n = 6	0.29	0.6	0	2
	Cortex	0%/n = 0	0.00	0	0	0
	Basal ganglia	4.2%/n = 1	0.04	0.2	0	1
	Hippocampus	16.7%/n = 4	0.20	0.5	0	2
	Corpus callosum	0%/n = 0	0.00	0	0	0
	Thalamus	4.2%/n = 1	0.04	0.2	0	1
AA	Whole brain	91.7%/n = 22	61.75	83.3	0	259
	Cortex	91.7%/n = 22	31.00	43.9	0	143
	Basal ganglia	62.5%/n = 15	10.30	16.9	0	50
	Hippocampus	91.7%/n = 22	12.80	15.8	0	48
	Corpus callosum	45.8%/n = 11	3.50	5.9	0	22
	Thalamus	58.3%/n = 14	4.50	6.3	0	20

The table shows the number of animals affected by erythrocyte thrombi, small perivascular bleeds and cerebral amyloid angiopathy (CAA) in the different brain regions (as percentage and total number of affected animals), related to histological analysis. The mean number of the respective pathology per animal is displayed, including standard deviation, minimum and maximum value (for erythrocyte thrombi the mean number refers to 50 fields of view per brain region, adding up to 250 fields of view for the whole brain; for small perivascular bleeds and CAA means refer to all investigated slices).