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. 2020 Jun 10;12(7):e12088. doi: 10.15252/emmm.202012088

Figure 2. BAM15 alters the expression of metabolic genes related to energy homeostasis.

Figure 2

  • A
    Heat map visualization of top 30 differentially regulated mRNA transcripts. Color represents significant downregulated (blue) or upregulated (red) mRNA expressed as a log2 fold change relative to vehicle corrected for the false discovery rate.
  • B
    Schematic illustration of differentially regulated mRNA transcripts involved in the AMPK signaling pathway. Structures highlighted in shades of red were differentially regulated by BAM15. Darker shades of red correlate with increased probability of activation. Structures highlighted in gray or with black borders were unaltered by BAM15.
  • C
    Pathway enrichment analysis of differentially regulated mRNA transcripts.