Table 2.
Diagnostic performance of standard breast MRI with complete FOV and dedicated axillary MRI
| Reader 1 | Reader 2 | |||
|---|---|---|---|---|
| T2W | T2W with DW imaging* | T2W | T2W with DW imaging* | |
| Standard breast MRI (n = 47) | ||||
| Sensitivity | 50.0% (4/8) | 50.0% (4/8) | 62.5% (5/8) | 50.0% (4/8) |
| [15.7–84.3] | [15.7–84.3] | [24.5–91.5] | [15.7–84.3] | |
| Specificity | 92.3% (36/39) | 94.9% (37/39) | 92.3% (36/39) | 92.3% (36/39) |
| [79.1–98.4] | [82.7–99.4] | [79.1–98.4] | [79.1–98.4] | |
| PPV | 57.1% (4/7) | 66.7% (4/6) | 62.5% (5/8) | 57.1% (4/7) |
| [18.4–90.1] | [22.3–95.7] | [24.5–91.5] | [18.4–90.1] | |
| NPV | 90.0% (36/40) | 90.2% (37/41) | 92.3% (36/39) | 90.0% (36/40) |
| [76.3–97.2] | [76.9–97.3] | [79.1–98.4] | [76.3–97.2] | |
| AUC | 0.72 | 0.73 | 0.78 | 0.72 |
| [0.53–0.92] | [0.54–0.92] | [0.60–0.97] | [0.53–0.91] | |
| Dedicated axillary MRI (n = 47) | ||||
| Sensitivity | 37.5% (3/8) | 25.0% (2/8) | 62.5% (5/8) | 62.5% (5/8) |
| [8.5–75.5] | [3.2–65.1] | [24.5–91.5] | [24.5–91.5] | |
| Specificity | 92.3% (36/39) | 87.2% (34/39) | 82.1% (32/39) | 92.3% (36/39) |
| [79.1–98.4] | [72.6–95.7] | [66.5–92.5] | [79.1–98.4] | |
| PPV | 50.0% (3/6) | 28.6% (2/7) | 44.6% (5/12) | 62.5% (5/8) |
| [11.8–88.2] | [3.7–71.0] | [15.2–72.3] | [24.5–91.5] | |
| NPV | 87.8% (36/41) | 85.0% (34/40) | 91.4% (32/35) | 92.3% (36/39) |
| [73.8–95.9] | [70.2–94.3] | [76.9–98.2] | [79.1–98.4] | |
| AUC | 0.65 | 0.57 | 0.73 | 0.78 |
| [0.46–0.83] | [0.39–0.75] | [0.53–0.92] | [0.60–0.97] | |
Data in parentheses are absolute numbers. Data in brackets are 95% confidence intervals
*The additional information of the DW MR images was used to adjust the initial score based on the T2W MR images. If the DW image score was unavailable, the T2W image score remained unchanged
Abbreviations: FOV, field of view; T2W, T2-weighted; DW, diffusion-weighted; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve