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. 2020 Jan 8;47(9):2155–2164. doi: 10.1007/s00259-019-04669-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Tau burden within spatial patterns differs by Aβ, APOE, and sex in older adults. We found significantly higher tau burden in some of the spatial patterns in Aβ-positive compared with Aβ-negative peers, APOE ε3ε3 compared with ε2ε3 carriers, and in women compared with men. Asterisk indicates significant differences between groups, after regressing out the effects of age, sex, education for Aβ groups; age, sex, education, and PiB DVR for APOE groups; and age, education, and PiB DVR for sex groups. All results were corrected for multiple comparisons using FDR (q < 0.05)