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Response to sodium nitroprusside (10−10 – 10−5 M) in isolated pressurized MCA from Sprague–Dawley rats during and after construction activities. Data are expressed as change from resting control diameter (CD) (µm; mean ± SEM). Value significantly different in new rats compared with responses during construction (inhouse rats; *, P < 0.05; ○, P < 0.005; ■, P < 0.0001) or in new rats compared with inhouse rats studied after construction (#, P < 0.05).
