Table 3.

VTE and bleeding complication rates by anticoagulation timing

Variable		< 24 Hours (n = 49)	24–72 Hours (n = 20)‡	> 24 Hours (n = 30)§	Odds ratio (95% CI)	p-value
Thromboembolism
	DVT	2 (4.1)	6 (30.0)	7 (23.3)	0.099 (0.018-0.548)	0.006‡
					0.140 (0.027-0.727)	0.009§
	PE	3 (6.1)	1 (5.0)	3 (10.0)	-	1.000‡/0.668§
	VTE	3 (6.1)*	7 (35.0)	9 (30.0)†	0.121 (0.027-0.535)	0.005‡
					0.152 (0.037-0.620)	0.008§
Bleeding
	Hematoma	0 (0)	0 (0)	0 (0)	-	N/A
	Seroma	0 (0)	0 (0)	0 (0)	-	N/A
	Dehiscence	2 (4.1)	0 (0)	0 (0)	-	1.000
Drain output
	TotalII (mL)	592	888	751	-	0.336‡/0.460§
	Average daily¶ (mL)	117	167	154	-	0.247‡/0.261§
	Drain duration (day)	4.45	4.15	4.19	-	0.512‡/0.640§

Values are presented as number (%) unless otherwise indicated.

CI, confidence interval; DVT, deep vein thrombosis; PE, pulmonary embolism; VTE, venous thromboembolism; N/A, not applicable. VTE refers to either a DVT, PE, or the simultaneous discovery of both in a single patient. Drain output data was available for 40, 16, and 26 patients or the early, standard, and standard+late groups, respectively.

^*2 Patients had DVT and PE in the early anticoagulation group.

^†1 patient had DVT and PE in the standard+late anticoagulation group.

^‡Comparison of early vs. standard anticoagulation groups.

^§Comparison of early vs. standard+late anticoagulation groups.

^IISum of daily drain outputs during entire hospital stay averaged by number of patients.

^¶Total drain output divided by number of days drain in place averaged by number of patients.