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. Author manuscript; available in PMC: 2020 Jul 7.
Published in final edited form as: Support Care Cancer. 2019 Oct 21;28(7):3061–3072. doi: 10.1007/s00520-019-05074-8

Table 3.

Adjusted levels (predictive margins) for any pain medication or any opioid receipt by cancer history, severity of pain interference, and selected respondent characteristics

Any pain medication Any opioid
Predictive margin 95% CI margin p value* Predictive margin 95% CI margin p value*
Pain interference
 Severe 38.1 36.3 39.9 < 0.001 25.3 23.7 27.0 < 0.001
 Moderate 19.5 18.6 20.4 < 0.001 9.0 8.3 9.7 < 0.001
 Mild/none 11.3 10.4 12.3 4.2 3.6 4.9
Cancer history
 Cancer 22.4 21.6 23.2 0.002 9.8 9.1 10.5 < 0.001
 No cancer 20.3 19.4 21.3 12.9 12.2 13.5
Cancer history, stratified by pain interference
 Severe
  Cancer 38.7 36.5 40.9 0.048 26.4 24.4 28.4 0.003
  No cancer 37.1 34.4 39.8 23.8 21.5 26.2
 Moderate
  Cancer 20.3 19.1 21.5 0.105 10.6 9.6 11.5 0.292
  No cancer 18.4 17.0 19.8 6.8 5.9 7.7
 Mild/none
  Cancer 12.6 11.3 14.0 0.001 5.3 4.4 6.2 < 0.001
  No cancer 9.6 8.3 10.9 2.8 2.0 3.5
Sex
 Male 19.8 18.9 20.7 11.0 10.3 11.7
 Female 23.1 22.2 24.0 < 0.001 12.2 11.5 12.8 0.034
Age group
 66–69 23.3 22.1 24.6 13.0 12.0 14.0
 70–74 22.6 21.4 23.7 0.353 12.5 11.6 13.5 0.598
 75–79 20.7 19.5 22.0 0.004 11.3 10.3 12.3 0.023
 80+ 18.9 17.7 20.2 < 0.001 9.4 8.5 10.3 < 0.001
Race/ethnicity
 White, non-Hispanic 22.6 21.7 23.4 13.0 12.3 13.6
 Black, non-Hispanic 20.5 18.6 22.5 0.078 10.8 9.4 12.3 0.03
 Hispanic 22.0 20.1 23.9 0.621 9.8 8.5 11.1 0.001
 Asian, other 17.0 15.5 18.6 < 0.001 7.9 6.7 9.0 < 0.001
Currently married
 Married 21.0 20.1 21.8 0.068 10.8 10.1 11.4 0.001
 Not married 22.2 21.2 23.2 12.6 11.8 13.3
Education
 < High school diploma 22.4 21.1 23.7 12.8 11.8 13.8
 High school diploma 21.5 20.4 22.6 0.291 11.6 10.7 12.4 0.091
 > High school diploma 20.9 20.0 21.9 0.087 10.8 10.0 11.5 0.001
Has a doctor ever told you that you have…
 Coronary artery disease 20.6 19.1 22.2 0.235 11.7 10.5 12.9 0.878
 Stroke 22.9 20.9 24.9 0.15 10.3 9.0 11.7 0.057
 Pulmonary disease 22.5 21.1 24.0 0.134 12.8 11.7 13.9 0.048
 Diabetes 23.7 22.5 24.9 < 0.001 12.0 11.2 12.9 0.12
 Depression 22.2 20.7 23.7 0.305 11.8 10.7 12.8 0.895
 Arthritis 24.3 23.4 25.2 < 0.001 12.6 12.0 13.2 < 0.001
 Sciatica 24.3 23.0 25.6 < 0.001 12.8 11.9 13.8 0.001
Poverty rates
 Low (0 to < 5%) 21.3 19.8 22.7 0.326 11.4 10.2 12.5 0.054
 5 to < 10% 21.0 19.9 22.2 0.175 11.0 10.1 11.9 0.004
 10 to < 20% 21.5 20.5 22.6 0.369 11.1 10.3 11.9 0.007
 High (20 to 100%) 22.3 20.9 23.7 13.1 12.0 14.2
Region
 Northeast 17.8 16.2 19.4 9.1 7.9 10.3
 South 22.8 20.7 24.8 < 0.001 12.6 11.0 14.2 0.001
 Central 22.1 20.8 23.4 < 0.001 11.6 10.7 12.6 0.003
 West 21.9 21.0 22.8 < 0.001 12.0 11.3 12.7 0.001
Part D Low income subsidy
 Full/partial 25.3 23.8 26.8 < 0.001 13.6 12.5 14.7 < 0.001
 None 20.3 19.6 21.1 10.9 10.3 11.4
Plan type
 HMO 21.6 20.9 22.2 11.5 11.0 12.0
 Other plan type 20.8 18.7 23.0 0.512 12.5 10.8 14.2 0.363
Proximity of death
 < 6 months from MHOS survey 26.4 22.8 30.1 0.004 17.4 14.5 20.3 < 0.001
 ≥ 6 months from MHOS survey 21.3 20.7 22.0 11.4 10.9 11.8
a

p values reported for comparison of predictive margins for each attribute compared with a reference category. HMO, health maintenance organization; MHOS, Medicare Health Outcomes Survey. Source: SEER-MHOS-Part D linked data, 2008–2012