Table 2.
Stratification Analysis for Association between WTAP Gene Genotypes and Hepatoblastoma Susceptibility
Variables |
rs1853259 (Case/Control) |
AOR (95% CI)a |
pa |
rs7766006 (Case/Control) |
AOR (95% CI)a |
pa |
Risk Genotypes (Case/Control) |
AOR (95% CI)a |
pa |
|||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AA/AG | GG | GG | GT/TT | 0–1 | 2 | |||||||
Age, Month | ||||||||||||
<17 | 128/555 | 37/86 | 1.85 (1.20–2.85) | 0.005 | 73/207 | 92/434 | 0.60 (0.43–0.85) | 0.005 | 93/435 | 72/206 | 1.63 (1.15–2.31) | 0.006 |
≥17 | 124/680 | 21/122 | 0.95 (0.58–1.57) | 0.840 | 52/272 | 93/530 | 0.90 (0.62–1.31) | 0.593 | 97/531 | 48/271 | 0.98 (0.67–1.43) | 0.930 |
Gender | ||||||||||||
Female | 106/517 | 21/78 | 1.31 (0.78–2.22) | 0.310 | 49/175 | 78/420 | 0.66 (0.45–0.99) | 0.044 | 80/420 | 47/175 | 1.41 (0.94–2.11) | 0.094 |
Male | 146/718 | 37/130 | 1.40 (0.93–2.10) | 0.106 | 76/304 | 107/544 | 0.78 (0.56–1.08) | 0.133 | 110/546 | 73/302 | 1.21 (0.87–1.68) | 0.256 |
Clinical Stages | ||||||||||||
I + II | 129/1,235 | 31/208 | 1.43 (0.94–2.18) | 0.094 | 68/479 | 92/964 | 0.67 (0.48–0.93) | 0.017 | 95/966 | 65/477 | 1.40 (1.00–1.95) | 0.051 |
III + IV | 79/1,235 | 10/208 | 0.75 (0.38–1.47) | 0.395 | 31/479 | 58/964 | 0.94 (0.60–1.48) | 0.788 | 60/966 | 29/477 | 0.97 (0.61–1.53) | 0.892 |
The results were in bold if the 95% confidence intervals (CIs) excluded 1, or p values were less than 0.05. AOR, adjusted odds ratio.
Adjusted for age and gender, omitting the corresponding stratify factor.