Table 4.

False-Positive Report Probability Analysis for Significant Findings

Genotype	OR (95% CI)	pa	Statistical Powerb	Prior Probability
				0.25	0.1	0.01	0.001	0.0001
rs1853259 GG versus AG/AA
<17 months	1.87 (1.21–2.87)	0.005	0.161	0.077	0.201	0.734	0.965	0.996
rs7766006 G > T
GT versus GG	0.70 (0.53–0.92)	0.010	0.714	0.039	0.108	0.571	0.931	0.993
GT/TT versus GG	0.74 (0.57–0.95)	0.017	0.769	0.062	0.164	0.684	0.956	0.995
<17 months	0.60 (0.42–0.85)	0.004	0.274	0.044	0.121	0.603	0.939	0.994
Female	0.66 (0.45–0.99)	0.043	0.483	0.212	0.447	0.899	0.989	0.999
Stage I + II	0.67 (0.48–0.94)	0.019	0.512	0.100	0.250	0.786	0.974	0.997
Risk Genotypes
2 versus 0	1.39 (1.02–1.88)	0.036	0.854	0.111	0.272	0.805	0.976	0.998
<17 months	1.64 (1.15–2.32)	0.006	0.318	0.052	0.141	0.644	0.948	0.995
Haplotypes
AGT versus GAT	1.56 (1.01–2.41)	0.043	0.491	0.208	0.441	0.897	0.989	0.999
AAG versus GAT	6.25 (1.38–28.29)	0.018	0.037	0.583	0.808	0.979	0.998	1.000

The results were in bold if the false-positive report probability was less than 0.200. OR, odds ratio; CI, confidence interval.

^aChi-square test was used to calculate the genotype frequency distributions.

^bStatistical power was calculated using the number of observations in each subgroup and the corresponding ORs and p values in this table.