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Altered expression of histone modifying enzymes in response to suppression of BRAFVE. (A) Normalized gene expression (FPKMs) of virally delivered Dox-regulated BRAFVE in primary, dormant and recurrent tumors resistant to Dox treatment. (B) Normalized gene expression (FPKM) of Ezh2, Suv38h1, Suv38h2,Ash2l, ASH2L, SYMD2, and PRMT5 in primary, dormant and recurrent tumors. Students T-tests were performed to assess significance.
