Fig. 3.

Integration of RNA-Seq, perfusion, and clinical trial research data for Pearson correlation analysis. Comparison of peripheral blood (PB) circulating cells and biomarkers (orange), MRI myocardial perfusion parameters (green), and human PB gene expression data (RNA-Seq) (black). The ΔLVEF response (red) is highlighted for an improved visual analysis of important correlations. The color scale, ranging from 1 to -1 in the upper panel (blue to red), represents the correlation between the different factors. The size of the dots represents the significance (p<0,01, p<0,05, and p>0,05; Pearson correlation) of the respective correlation (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.).