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Comparison of CB1 Binding to Different Ligands
Analysis of the ligand binding pocket (A) AM6538@CB1 (5TGZ) and (B) AM11542@CB1 (5XRA). (C) Comparison of the agonist-bound (blue) and antagonist-bound (light blue) CB1. (D) Superposition of FUB@CB1 (navy) and AM11542@CB1 (blue). Data used to prepare the figures were obtained from Hua et al. (2016), Figures 4A; Hua et al. (2017), Figure 4B; and Krishna Kumar et al. (2019), Figure 4D.
