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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Prostate. 2019 Sep 10;79(16):1811–1822. doi: 10.1002/pros.23906

FIGURE 4. AR and ARv7 Co-expression in PRCA Progression.

FIGURE 4.

A. Prostate composite images show AR+/ARv7− nuclei (red), AR−/ARv7+ nuclei (green), AR+/ARv7+ nuclei (yellow), and AR−/ARv7− nuclei (blue) at all stages of PRCA progression.

B. Quantification of the AR+/ARv7− population (red) shows a significant increase in PRCA compared to BENIGN (p<0.01).

C. Quantification of the AR−/ARv7+ population (green) shows a significant increase in METS compared to BENIGN (p<0.001).

D. Quantification of the AR+/ARv7+ population (yellow) shows a significant increase in METS compared to BENIGN (p<0.05), and a slight increase in HGPIN compared to BENIGN (p=0.07).

E. Prostate composite images show AR−/ARv7− nuclei (blue) shows a significant increase in PRCA compared to BENIGN (p<0.05).