Table 1.

Associations between Numb expression and patient and tumour characteristics

Factors	Triple‐negative tumours (n = 125)	Retained Numb n = 64 (51.2%)	Reduced and Deficient Numb n = 61 (48.8%)	P value
Age, years
≤50	76	42	34	0.2796
>50	49	22	27
Tumour size
≤2 cm	54	26	28	0.5911
>2 cm	71	38	33
Lymph node status
Positive(n > 0)	41	27	23	0.6091
Negative(n = 0)	84	37	38
Histological type
DCIS	4	2	2	0.5762
IDC	112	57	55
Medullary	2	0	2
Other	6	4	2
Missing	1	1	0
Ki67
≤14%	10 (8%)	9 (14%)	1 (1.6%)	0.0171*
>14%	115 (92%)	55 (86%)	60(98.4%)

The categorical variables were reported as numbers (n) and percentages of the total (%), and chi‐square test and Fisher's exact test were used to test the difference. The data analysis for this study was generated using SAS 9.4 software (Copyright^© 2016 SAS Institute Inc Cary). Significant difference was determined at the α level of 0.05. All P values were calculated using chi‐square test, except when calculating correlation between histological type, Ki67 and Numb expression when Fisher's exact was used. There is no significant difference in age, tumour size, lymph node status, histological type between the retained Numb group and reduced and deficient Numb group. The per cent of Ki67 > 14% in retained Numb group was significantly lower than that in the reduced and deficient Numb group (86.00% vs. 98.40%, P = .0171).

Abbreviations: DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma.

^*The P value is significant.