Figure 7.

miR-205 attenuated the RunX2-mediated proliferation, migration, invasion, and non-anchored growth ability of MCF-7 cells. (A) MTT, (B) migration, (C) invasion and (D) soft agar colony formation assays were performed on cells transfected with miR-negative control (NC) mimic, LV- RunX2 , miR-205 mimic, or cotransfected with miR-205+RunX2 mimic. Nontransfected MCF-7 cells were used as controls. *P<0.05, **P<0.01, vs miR-205 mimic.One-way ANOVA was used for comparisons among multiple groups.