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. 2020 Jun 1;10(6):1691–1709.

Figure 2.

Figure 2

Correlation between CMTM6 and NRP1 in OSCC samples and cell lines. (A) qRT-PCR analysis of CMTM6 and NRP1 mRNA expression in 50 OSCC tumors (T) and peritumoral oral tissues (NT). (B) Representative Western blotting analysis of CMTM6 and NRP1 protein expression. (C, D) Scatter plots show a positive correlation between CMTM6 and NRP1 at the mRNA (C) and protein (D) levels in 50 pairs of OSCCs (r = 0.4314, P < 0.0001 and r = 0.4957, P < 0.001). (E) Expression correlation between CMTM6 and NRP1 mRNA expression in the TCGA HNSCC database (starBase v3.0 project). Correlation was analyzed using Spearman’s correlation coefficient test, r = 0.394, P < 0.001, n = 502. (F) Quantification of CMTM6 and NRP1 mRNA expression levels using qRT-PCR analysis in 6 OSCC cell lines and human normal oral keratinocytes (HOK) cells. *P < 0.05, **P < 0.01, ***P < 0.001.