Fig. 1.

Dermal fibroblast heterogeneity. Hierarchy of murine dermal fibroblast subpopulations and their identifying molecular markers over the course of development and differentiation. Lineage/cell surface markers shown in this figure are based on data presented in the following publications: Driskell and Watt,⁷ Driskell et al,¹² Borrelli et al 2020 (unpublished), and Rinkevich et al.¹⁰ PDGFRa, platelet-derived growth factor receptor alpha; Sox2, SRY-box transcription factor 2; Lrig1, leucine-rich repeats and immunoglobulin-like domains 1; FSP1, fibroblast-specific protein 1; Col1, collagen type 1; En-1, engrailed homeobox 1; Prrx-1, paired related homeobox 1; Dlk1, delta-like non-canonical notch ligand 1; Dermo1=Twist2, Twist-related protein 2; Col1a2, collagen type 1 alpha 2 chain; Sca1, stem cell antigen 1