Table 4.
Factors predicting OS
| Items | Cox’s proportional hazard regression model | |||
|---|---|---|---|---|
| P value | HR | 95%CI | ||
| Lower | Higher | |||
| Univariate Cox’s regression | ||||
| CCT6A high | <0.001 | 1.952 | 1.515 | 2.516 |
| Age (>60.0 years) | 0.156 | 1.199 | 0.933 | 1.541 |
| Male | 0.657 | 1.069 | 0.797 | 1.432 |
| History of smoke | 0.149 | 0.832 | 0.648 | 1.068 |
| History of drink | 0.460 | 1.101 | 0.853 | 1.421 |
| Hypertension | 0.454 | 0.906 | 0.698 | 1.174 |
| Hyperlipidemia | 0.590 | 0.928 | 0.706 | 1.219 |
| Diabetes | 0.308 | 0.834 | 0.588 | 1.183 |
| Poor differentiation | 0.001 | 1.368 | 1.133 | 1.652 |
| Tumor size (>5.0 cm) | <0.001 | 1.605 | 1.248 | 2.064 |
| LYN metastasis | <0.001 | 3.081 | 2.385 | 3.979 |
| Higher TNM stage | <0.001 | 1.446 | 1.244 | 1.682 |
| Abnormal CEA (>5.0 ng/mL) | <0.001 | 1.880 | 1.444 | 2.447 |
| Forward stepwise multivariate Cox’s regression | ||||
| CCT6A high | <0.001 | 1.779 | 1.378 | 2.298 |
| Poor differentiation | 0.003 | 1.360 | 1.113 | 1.663 |
| LYN metastasis | <0.001 | 2.825 | 2.183 | 3.656 |
| Abnormal CEA (>5.0 ng/mL) | <0.001 | 1.816 | 1.393 | 2.368 |
Factors predicting OS were analyzed by univariate Cox’s proportional hazard regression models. The factors with P < 0.05 in univariate Cox’s regression were further analyzed in forward stepwise multivariate Cox’s regression. OS overall survival; HR hazard ratio; CI confidence interval; CCT6A chaperonin containing TCP1 subunit 6A; LYN lymph node; CEA carcinoembryonic antigen