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. 2020 May 7;22(2):733–738. doi: 10.3892/mmr.2020.11139

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Syntenin-siRNA transfection increases the expression of melanogenesis-related proteins in PIG1 immortalized human melanocytes. After transfection with syntenin-siRNA, western blotting was performed to examine the protein expression levels of catalytic component Tyr, melanosome structural protein Pmel and transcription factor MITF. Results were normalized against β-actin expression. *P<0.05 vs. Blank. MITF, microphthalmia-associated transcription factor; NC, negative control; Pmel, pre-melanosomal protein; siRNA, small interfering RNA; Tyr, tyrosinase.