Table III.
GO analysis of downregulated genes associated with glioblastoma multiforme.
| Category | Term | Count | P-value |
|---|---|---|---|
| GOTERM_BP_DIRECT | GO:0007268~chemical synaptic transmission | 54 | 1.09E-42 |
| GOTERM_BP_DIRECT | GO:0034765~regulation of ion transmembrane transport | 18 | 1.37E-11 |
| GOTERM_BP_DIRECT | GO:0007269~neurotransmitter secretion | 12 | 1.33E-09 |
| GOTERM_BP_DIRECT | GO:0007187~G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 11 | 7.02E-09 |
| GOTERM_BP_DIRECT | GO:0007214~gamma-aminobutyric acid signaling pathway | 8 | 7.68E-08 |
| GOTERM_CC_DIRECT | GO:0005886~plasma membrane | 162 | 7.00E-26 |
| GOTERM_CC_DIRECT | GO:0005887~integral component of plasma membrane | 85 | 4.55E-23 |
| GOTERM_CC_DIRECT | GO:0045211~postsynaptic membrane | 32 | 1.74E-19 |
| GOTERM_MF_DIRECT | GO:0005230~extracellular ligand-gated ion channel activity | 11 | 1.99E-10 |
| GOTERM_MF_DIRECT | GO:0004890~GABA-A receptor activity | 9 | 6.42E-10 |
| GOTERM_MF_DIRECT | GO:0005516~calmodulin binding | 17 | 3.29E-07 |
GO, Gene Ontology; BP, biological process; CC, cellular component; MF, molecular function.