Figure 6. Inverse immunohistochemical staining of MHC class I and phospho-AKT-S473 in human squamous cell carcinoma.
Squamous cell carcinomas of the head and neck were stained for MHC class I (top panels of each example) and phospho-AKT-S473 (bottom panels of each example). Regions of lower staining (black outline) of MHCI correspond to regions of highest phospho-AKT staining (yellow outlines) and vice versa. In some images, such regions are indicated using double headed arrows. Areas of stroma are indicated with brackets in some of the tumor images.