Fig. 3.

NCSTN promotes tumor growth and metastasis in vivo. a, b Tumor volume and weight of subcutaneous xenografts in nude mice injected with indicated HCCLM3 and Hep3B cells. c, d Fluorescence images of intrahepatic metastatic foci in liver orthotopic-implanted HCC models with indicated HCC cells. e, f Representative images of corresponding hematoxylin and eosin staining of liver orthotopic-implanted HCC models. Scale bars, 100 μm. g, h Fluorescence images of lung metastatic foci in lung metastasis models with indicated HCCLM3 and Hep3B cells. i, j Representative images of corresponding hematoxylin and eosin staining of lung metastasis models. Scale bars, 100 μm. *p < 0.05, **p < 0.01, ***p < 0.001