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CIH-induced liver fibrosis. After exposing rats to CIH for 4 weeks, liver tissues were harvested and subjected to Sirius red staining. (A) Con group, (B) CIH group, (C) CIH-Vector and (D) CIH-TLR4 group. Representative images of immunohistochemistry. Magnification, ×400. Con, control; CIH, chronic intermittent hypoxia; CIH-Vector group, CIH + empty vector lentivirus; CIH-TLR4 group, CIH + TLR4 shRNA lentivirus; shRNA, short hairpin RNA; TLR4, Toll-like receptor 4.
