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. 2020 May 21;22(2):886–894. doi: 10.3892/mmr.2020.11167

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Copyright: © Lian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of TIM-3 overexpression on proliferation and migration in PDGF-BB-stimulated HASMCs. (A) Proportion of EdU-positive cells. (B) Number of migratory cells. (C) Ratio of wound healing. (D) EdU, (E) Transwell and (F) wound healing assays were performed to assess proliferation and migration in PDGF-BB-stimulated (20 ng/ml) HASMCs in the presence or absence of LV-TIM-3 (n=5; scale bar, 100 µm). **P<0.01 as indicated. TIM-3, T-cell immunoglobulin and mucin domain 3; PDGF-BB, platelet-derived growth factor-BB; HASMCs, human artery vascular smooth muscle cells; LV, lentivirus.