Table 1.
Physicochemical properties of RdRP protein (YP_009725307.1)
| Physiochemical properties | RdRP COVID-19 | Amino acid composition | No. | Percent composition (%) |
|---|---|---|---|---|
| Molecular weight | 106,660.24 | Ala (A) | 64 | 6.90 |
| No. of amino acids | 932 | Arg (R) | 43 | 4.60 |
| Theoretical pI | 6.14 | Asn (N) | 56 | 6.00 |
| Instability index | 28.32 | Asp (D) | 75 | 8.00 |
| No. of negatively charged (Asp + Glu) | 106 | Cys (C) | 29 | 3.10 |
| No. of positively charged (Arg + Lys | 94 | Gln (Q) | 28 | 3.00 |
| aliphatic index | 78.43 | Glu (E) | 31 | 3.30 |
| Grand average of hydropathicity | −0.224 | Gly (G) | 45 | 4.80 |
| Estimated half-life (mammalian reticulocytes, in vitro) | 1.9 h | His (H) | 27 | 2.90 |
| Atomic composition | Ile (I) | 33 | 3.50 | |
| C | 4792 | Leu (L) | 83 | 8.90 |
| H | 7265 | Lys (K) | 51 | 5.50 |
| N | 1259 | Met (M) | 25 | 2.70 |
| O | 1401 | Phe (F) | 57 | 6.10 |
| S | 54 | Pro (P) | 30 | 3.20 |
| Formula | C4792H7265N1259O1401S54 | Ser (S) | 53 | 5.70 |
| Total number of atoms | 14,771 | Thr (T) | 61 | 6.50 |
| Trp (W) | 9 | 1.00 | ||
| Tyr (Y) | 58 | 6.20 | ||
| Val (V) | 74 | 7.90 | ||
| Pyl (O) | 0 | 0.00 | ||
| Sec (U) | 0 | 0.00 |