Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 15;22(2):1179–1186. doi: 10.3892/mmr.2020.11228

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Tao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Overexpression of Septin4 increases cytoskeleton destruction in hFOB 1.19 cells treated with a high melatonin concentration. hFOB 1.19 cells were untreated or treated with 4 mmol/l melatonin for 48 h. F-actin was visualized using phalloidin and the nucleus was stained using DAPI. The images were captured using fluorescence microscopy (×20) and an image of the two stains merged was shown. The yellow arrow represents the F-actin cytoskeleton and the red arrow depicts the destroyed cytoskeleton. The histogram indicates the percentage of cytoskeleton-destroyed cells among the total cells. **P<0.01, vs. NC group. GRP, glucose-regulated protein; NC, negative control; F-actin, fibrillar actin.