Table IV.

SPRT classification process for relative haplotype dosage analysis of type α single nucleotide polymorphisms near the p-ter of chromosome 16 in family 1.

Position	Hap I count	Hap II count	Hap I cum.	Hap II cum.	Total reads	Hap I fraction	Upper boundary	Lower boundary	SPRT
234632	23	25	23	25	48	0.4792	0.8506	0.0569	Unclassified
256278	84	108	107	133	240	0.4458	0.5331	0.3744	Unclassified
281299	97	95	204	228	432	0.4722	0.4978	0.4096	Unclassified
281885	85	109	289	337	626	0.4617	0.4842	0.4233	Unclassified
306243	56	68	345	405	750	0.4600	0.4791	0.4283	Unclassified
311853	84	110	429	515	944	0.4544	0.4739	0.4336	Unclassified
312253	89	104	518	619	1,137	0.4556	0.4705	0.4370	Unclassified
312635	94	95	612	714	1,326	0.4615	0.4681	0.4394	Unclassified
315557	92	101	704	815	1,519	0.4635	0.4663	0.4412	Unclassified
317393	89	90	793	905	1,698	0.4670	0.4650	0.4425	Hap I
319761	97	96	890	1,001	1,891	0.4707	0.4638	0.4437	Hap I
336660	98	95	988	1,096	2,084	0.4741	0.4629	0.4446	Hap I
377617	81	89	1,069	1,185	2,254	0.4743	0.4622	0.4453	Hap I
390780	96	97	1,165	1,282	2,447	0.4761	0.4615	0.4460	Hap I
423420	89	87	1,254	1,369	2,623	0.4781	0.4610	0.4465	Hap I
427516	72	74	1,326	1,443	2,769	0.4789	0.4606	0.4469	Hap I
641445	84	105	1,410	1,548	2,958	0.4767	0.4602	0.4473	Hap I
651517	98	96	1,508	1,644	3,152	0.4784	0.4598	0.4477	Hap I
674029	87	97	1,595	1,741	3,336	0.4781	0.4594	0.4480	Hap I
678843	88	90	1,683	1,831	3,514	0.4789	0.4592	0.4483	Hap I
878161	88	106	1,771	1,937	3,708	0.4776	0.4589	0.4486	Hap I
880431	85	109	1,856	2,046	3,902	0.4757	0.4586	0.4489	Hap I
928867	87	94	1,943	2,140	4,083	0.4759	0.4584	0.4491	Hap I
940706	85	102	2,028	2,242	4,270	0.4749	0.4582	0.4493	Hap I

SPRT, sequential probability ratio test; hap, haplotype.