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. 2020 May 15;22(2):723–732. doi: 10.3892/mmr.2020.11149

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Copyright: © Gao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — lncRNA FLVCR1-AS1 expression is increased in human GBM samples and is associated with poor prognosis. (A) Heat map demonstrating the differential expression of lncRNAs from TCGA GBM database. (B) Gene expression levels of FLVCR1-AS1 in TCGA GBM cohort compared with the normal cohort. (C) GO analysis of genes positively associated with FLVCR1-AS1 from TCGA GBM datasets. (D) Kaplan-Meier curve of overall survival in patients with GBM; high levels of FLVCR1-AS1 are associated with poorer prognosis (n=151). (E) High expression levels of FLVCR1-AS1 in patients with GBM (n=50), compared with matched adjacent normal tissues (reverse transcription-quantitative PCR analysis). Each experiment was performed in triplicate. ***P<0.001. FLVCR1-AS1, Feline Leukemia Virus Subgroup C Cellular Receptor 1 Antisense RNA 1; GBM, glioblastoma; TCGA, The Cancer Genome Atlas; GO, Gene Ontology.