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Knockdown and overexpression of TREM2 in HK-2 cells. Relative (A) mRNA and (B) protein expression levels of TREM2 were suppressed by siTREM2 RNAs. ***P<0.001 vs. siNC. Relative (C) mRNA and (D) protein expression levels of TREM2 in HK-2 cells overexpressing TREM2. ***P<0.001 vs. oeNC. TREM2, triggering receptor expressed on myeloid cells 2; si, small interfering RNA; oe, overexpression; NC, negative control.
