Figure 4.

HBX targets TREM2 in HK-2 cells. (A) Apoptosis rate of oeHBX cells was reduced by siTREM2-1 and siTREM2-2. (B) Western blot analysis was used to examine the protein expression levels of TREM2, Survivin, cleaved caspase3 and NF-κB in the different cells. **P<0.01 and ***P<0.001 vs. oeNC. ^#P<0.05 and ^###P<0.001 vs. oeHBX + siNC. HBX, hepatitis B virus X; TREM2, triggering receptor expressed on myeloid cells 2; oe, overexpression; si, small interfering RNA; NC, negative control; H3, histone H3.