Figure 5.

Overexpression of TREM2 reduces the translocation of NF-κB to the nucleus in HK-2 cells. (A) ECH reduced the apoptosis rate of oeTREM2 cells. (B) Western blotting was used to examine the protein expression levels of TREM2, Survivin, cleaved caspase3 and NF-κB in the different cells. *P<0.05 and ***P<0.001 vs. oeNC. ^#P<0.05 and ^###P<0.001 vs. oeTREM2 + siNC. TREM2, triggering receptor expressed on myeloid cells 2; ECH, echinacoside; oe, overexpression; NC negative control; E10, 10 mg/l ECH.